教授/博导

山东省泰山学者特聘教授，享受国务院特殊津贴。兼任中国遗传学会基因组专业委员会委员，中国生物工程学会海洋生物工程专业委员会委员，中国海洋湖沼/动物学会鱼类学分会理事，中国水产学会生物技术专业委员会委员等职务。

学习工作简历：

1979.9-1983.7：山东海洋学院海洋生物系，获理学学士学位

1983.9-1986.7：山东海洋学院海洋生物系，获理学硕士学位

1986.7-1994.2：中国海洋大学海洋生命学院，助教、讲师

1994.10-1998.2：日本广岛大学生物生产学部，获哲学博士学位

1998.3-1999.2：美国威廉马丽大学海洋研究所，博士后

1999.3-2001.2：日本水产养殖研究所，科技厅特别研究员（博士后）

1999.12-现在：中国海洋大学海洋生命学院教授、博士生导师

2003.10-2011.7期间，任中国海洋大学海洋生命学院院长

2019.10-现在：中国海洋大学三亚海洋研究院，教授

主要科研领域：

研究方向为热带海洋生物种质资源开发与种业工程，主要从事海洋生物遗传学和基因组学研究，在鱼类分子遗传学及优良品种选育、鱼类染色体组操作与性别决定机制、鱼类基因组学和功能基因研究、鱼类胚胎干细胞和生殖干细胞分离培养及借腹生子研究等方面取得了系列研究成果。

1. 在我国率先建立了星鲽和石鲽的生殖调控人工繁殖技术体系，实现了星鲽和石鲽的人工繁殖。

2. 建立了鱼类染色体显微切割技术、半滑舌鳎性别鉴定技术、舌鳎和牙鲆性别控制育种技术。

3. 开展了牙鲆分子和细胞遗传学研究，建立了牙鲆BLUP育种技术体系。

4. 开展了海水鱼类胚胎干细胞和生殖干细胞研究，构建了干细胞特异性识别载体，成功实现了胚胎干细胞和生殖干细胞的识别和分离，初步建立了海水鱼类借腹生子技术。

5. 完成了牙鲆单倍体和许氏平鲉的基因组分析，解明了牙鲆底栖视觉适应的分子机制，在国内首次解析了鱼类卵胎生的进化特征，证实许氏平鲉繁殖方式是从卵胎生向真正的胎生进化过程中的一种过渡类型。

近年来承担完成国家级“863”课题、国家自然科学基金、省部级重大课题数十项；已发表论文200余篇，其中SCI收录160余篇；获专利14项，国家知识产权2项，获省部级奖励4项。

1. Haiyang Yu, Yujue Wang, Chaofan Jin, Yuxiang Liu, Yan He and Quanqi Zhang*. 2020. The functional differentiation of four smad4 paralogs in TGF-β signaling pathway of Japanese flounder (Paralichthys olivaceus). Cellular Signalling, 71(2020): 109601. Doi: 10.1016/j.cellsig.2020.109601.

2. Kai Zhang, Yuxiang Liu, Xiumei Liu, Meiting Peng, Jinxiang Liuet and Quanqi Zhang*. 2019. A functional polymorphism in the promoter of RhoB is associated with susceptibility to Vibrio anguillarum in turbot (Scophthalmus maximus). Fish and Shellfish Immunology, 93: 269-277. Doi: 10.1016/j.fsi.2019.07.024.

3. Yan He, Yue Chang, Lisui Bao, Mengjun Yu, Rui Li, Jingjing Niu, Guangyi Fan, Weihao Song, Inge Seim, Yating Qin, Xuemei Li, Jinxiang Liu, Xiangfu Kong, Meiting Peng, Minmin Sun, Mengya Wang, Jiangbo Qu, Xiaobing Liu, Xiaolong Wu, Xuangang Wang, Xi Zhao, Xuliang Wang,Yaolei Zhang, Jiao Guo, Yang Liu, Kaiqiang Liu, Yilin Wang, He Zhang, Longqi Liu, Xubo Wang, Haiyang Yu, Jie Cheng, Zhigang Wang, Xun Xu, Jian Wang, Huanming Yang, Xin Liu, Quanqi Zhang* and Jie Qi*. 2019. A chromosome-level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birth. Molecular Ecology Resources, 2019; 00: 1-13. Doi: 10.1111/1755-0998.13034.

4. Jinxiang Liu, Chaofan Jin, Xinxin Du, Yuezhong Liu, Yan He, Quanqi Zhang*. 2019. Transcriptome profiling insights the feature of sex reversal induced by high temperature in tongue sole Cynoglossus semilaevis. Frontiers in Genetics, 10: 522. Doi: 10.3389/fgene.2019.00522.

5. Kai Zhang; Miao Han; Yuxiang Liu; Xiaohan Lin; Xiumei Liu; He Zhu; Yan He; Quanqi Zhang; Jinxiang Liu*. 2019. Whole-Genome resequencing from bulked-segregant analysis reveals gene set based association analyses for the Vibrio anguillarum resistance of turbot (Scophthalmus maximus). Fish & Shellfish Immunology, 88: 76-83. Doi: 10.1016/j.fsi.2019.02.041.

6. Yan Sun, Jinxiang Liu, Bo Wang, Xiumei Liu, Xinxin Du, Yuxiang Liu, Quanqi Zhang*. 2019. Klf4 could be activated by Pou5f3/Stat3 to induce the expression of Nanog in Japanese flounder. Gene, 687: 56-63. Doi: 10.1016/j.gene.2018.11.029.

7. Zan Li, Xiumei Liu, Jinxiang Liu, Kai Zhang, Haiyang Yu, Yan He, Xubo Wang, Jie Qi, Zhigang Wang and Quanqi Zhang*. 2018. Transcriptome profiling based on protein-protein interaction networks provides a core set of genes for understanding blood immune response mechanisms against Edwardsiella tarda infection in Japanese flounder (Paralichthys olivaceus). Developmental and Comparative Immunology, 78:100-113. Doi: 10.1016/j.dci.2017.09.013.

8. Bo Wang, Xinxin Du, Huizhen Wang, Chaofan Jin, Chen Gao, Jinxiang Liu, Quanqi Zhang*. 2019. Comparative studies on Duplicated TDRD7 paralogs in Teleosts: molecular evolution caused neofunctionalization. Comparative Biochemistry and Physiology, Part D: Genomics & Proteomics, 30, 347-357. Doi:10.1016/j.cbd.2019.04.006.

9. Xinxin Du, Xiaobing Liu, Kai Zhang, Yuxiang Liu, Jie Cheng, Quanqi Zhang*. 2018. Discovery and functional characterization of microRNAs and their potential roles for gonadal development in spotted knifejaw, Oplegnathus punctatus. Comparative Biochemistry and Physiology, Part D: Genomics & Proteomics. 28 (2018), 1-8. Doi: 10.1016/j.cbd.2018.05.002.

10. Jun Zhao, Bo Wang, Haiyang Yu, Yujue Wang, Xiaobing Liu, Quanqi Zhang*. 2018. tdrd1 is germ cell-specific and sexually dimorphically expressed gene in Paralichthys olivaceus. Gene, 673: 61–69. Doi: 10.1016/j.gene.2018.06.043.