Affiliation: Prof. Zhang Zhifeng

The Laboratory of Tropical Marine Germplasm Resources and Breeding Engineering, SANYA Oceanographic Institution of the Ocean University of CHINA (SOI-OUC)

Email: zzfp107@ouc.edu.cn

Education experiences:

1996.9 - 1999.6 Ph.D in Developmental Genetics, Ocean University of China.

1986.9 - 1989.6 M. Sc. in Marine Invertebrate Embryology, Ocean University of Qingdao.

1982.9 - 1986.6 B. Sc. in Marine Biology, Ocean College of Shandong.

Research experiences:

2020.04 - present Professor in SANYA Oceanographic Institution of the Ocean University of CHINA.

2003.12 - present Professor in Ocean University of China.

1989.7 - 2003.12 Assistant- Lecturer- Associate professor in Ocean University of China

2002.3 - 2003.2 Foreign Postdoctoral in National Yoesu University of Korea.

2005.3 - 2006.2 Visiting Scholar in National Yoesu University of Korea.

Research Interests：

Our group is mainly engaging in animal reproduction and development; Animal breeding; Animal development and antistress biology
Reproduction and Development – We use marine economic invertebrates as animal models and utilize the theories and experimental techniques of developmental biology, genetics and cell biology, to understand the mechanism of germline differentiation, sex differentiation, and genesis and functional establishment of key organs, so as to provide support data for the breeding practices of relevant species.
Animal development and antistress – We use immunology, molecular biology and various omics techniques to study the genetic and molecular mechanism of the antistress system establishment during animal development.
Research tool and platform building – To carry out the functional gene study involved in animal reproduction, development and antistress, we have established the essential tools and research platform.
Publications：

1. Xitan Hou, Maokai Wei, Qi Li, Tingting Zhang, Di Zhou, Dexu Kong, Yueyang Xie, Zhenkui Qin* and Zhifeng Zhang*. Transcriptome analysis on larval segment formation and secondary loss in the echiuran worm Urechis unicinctus. International Journal of Molecular Sciences (Int. J. Mol. Sci.), 2019, 20: 1806. doi:10.3390/ijms20081806 2019-4-12.

2. Shaoshuai Liang, Danwen Liu, Xixi Li, Maokai Wei, Xiaohan Yu, Qi Li, Huixin Ma, Zhifeng Zhang*, Zhenkui Qin*. Sox2 participates in spermatogenesis of Zhikong scallop Chlamys farreri. Scientific Reports, 2019，9:76. DOI:10.1038/s41598-018-35983-3

3. Xueyu Li^#, Xiaolong Liu^#, Zhenkui Qin, Maokai Wei, Xitan Hou, Tingting Zhang, Zhifeng Zhang*. A novel transcription factor Rwdd1 and its SUMOylation inhibit the expression of sqr, a key gene of mitochondrial sulfide metabolism in Urechis unicinctus. Aquatic toxicology, 2018, 204: 180-189.

4. Aichang Ji, Xueyu Li, Sha Fang, Zhenkui Qin, Chongming Wang, Zhifeng Zhang* Primary culture of Zhikong scallop Chlamys farreri hemocytes as an in vitro model for immune response detection. Diseases of Aquatic Organisms, 2017, Vol. 125: 217–226. https://doi.org/10.3354/dao03145 IF: 1.549

5. Yang Dandan *, Zhang Zhifeng *, Shaoshuai Liang, Qiankun Yang, Yingrui Wang, Zhenkui Qin**. (2017) A novel role of Krüppel-like factor 4 in Zhikong scallop Chlamys farreri during spermatogenesis. PLoS ONE, 12(6): e0180351. https://doi.org/10.1371/journal.pone.0180351

6. Xiaoyu Ma, Xiaolong Liu, Di Zhou, Yajiao Bai, Beibei Gao, Zhifeng Zhang*, Zhenkui Qin*. The NF- kB pathway participates in the response to sulfide stress in Urechis unicinctus. Fish & Shellfish Immunology, 2016, 58: 229-238.

7. Yanjie Zhang, Huawei Mu, Stanley C. K. Lau, Zhifeng Zhang∗ and Jian-Wen Qiu*. Sperm proteome of Mytilus galloprov incialis: Insights into the evolution of fertilization proteins in marine mussels. Proteomics, 2015, 15, 4175–4179. DOI 10.1002/pmic.201500066.

8. Xiaolong Liu, Litao Zhang, Zhifeng Zhang*, Xiaoyu Ma and Jianguo Liu. Transcriptional response to sulfide in the Echiuran Worm Urechis unicinctus by digital gene expression analysis. BMC Genomics, 2015, 16: 829-842 DOI 10.1186/s12864-015-2094-z.

9. BI Ying, ZHANG Bin, ZHANG Zhifeng*, QIU Jian-Wen*. Seasonality of gametogenesis in the host sea anemone Entacmaea quadricolor in Hong Kong. Journal of Ocean University of China. 2015, 14 (1): 143-148. DOI 10.1007/s11802-015-2349-y ISSN 1672-5182, 2015 14. http://www.ouc.edu.cn/xbywb.

10. Liu Jianguo, Zhifeng Zhang*, Xiaoshi Ma, Shaoshuai Liang, Dandan Yang. Characteristics of 17β-hydroxysteroid dehydrogenase 8 and its potential role in gonads of the Zhikong scallop Chlamys farreri. The Journal of Steroid Biochemistry and Molecular Biology, 2014, 141, 77-86.